Exploring structure-activity data using the landscape paradigm
نویسندگان
چکیده
منابع مشابه
Exploring the structure and function paradigm.
Advances in protein structure determination, led by the structural genomics initiatives have increased the proportion of novel folds deposited in the Protein Data Bank. However, these structures are often not accompanied by functional annotations with experimental confirmation. In this review, we reassess the meaning of structural novelty and examine its relevance to the complexity of the struc...
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ژورنال
عنوان ژورنال: Wiley Interdisciplinary Reviews: Computational Molecular Science
سال: 2012
ISSN: 1759-0876
DOI: 10.1002/wcms.1087